2,3-Dichloro-1-propanol

CAS: 616-23-9

Ref. 3D-FD21611

Product Information

• Name: 2,3-Dichloro-1-propanol
• Synonyms: Glycerol-?,?-dichlorohydrin2,3-Dichloropropanol, (2R)-2,3-dichloropropan-1-ol, (2S)-2,3-dichloropropan-1-ol, (RS)-2,3-Dichloro-1-propanol, 1,2-Dichloro-3-Propanol, 1,2-Dichlorohydrin, 1,2-Dichloropropanol-3, 1-Propanol,2,3-Dichloro-, 2,3-Dichloro-1-Propano, 2,3-Dichlorohydrin, 2,3-Dichloropropanol, 2,3-Dichloropropyl Alcohol, 2,3-dichloro-1-Propanol, Alpha,Beta-Dichlorohydrin, B-Dichlorohydrin, Beta,Gamma-Dichlorohydrin, Beta-Dichlorohydrin, Glycerol 1,2-Dichlorohydrin, Glycerol Alpha,Beta-Dichlorohydrin, Glycerol α,β-dichlorohydrin, α,β-Dichlorohydrin, β,γ-Dichlorohydrin
• CAS: 616-23-9

Description

2,3-Dichloro-1-propanol is a metabolic byproduct of chlorinated solvents. It has been shown to be toxic to mitochondria and can cause mitochondrial membrane potential disruption in rat liver cells. The chemical reacts with fatty acids to form a reactive carbonyl group that can react with the hydrogen bond of membrane phospholipids. This reaction disrupts the structure of the lipid bilayer, leading to mitochondrial degeneration. 2,3-Dichloro-1-propanol also reacts with glutathione and carbonic anhydrase, which leads to the formation of reactive intermediates that react with DNA or proteins. These reactions are responsible for the observed toxicity effects in animals.

• Brand: Biosynth

Chemical properties

• Molecular weight: 128.98 g/mol
• Formula: C₃H₆Cl₂O
• Purity: Min. 95%
• Color/Form: Colourless Liquid
• InChI: InChI=1S/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2
• InChI key: InChIKey=ZXCYIJGIGSDJQQ-UHFFFAOYSA-N
• SMILES: OCC(Cl)CCl