2,6-Dichlorohydroquinone

CAS: 20103-10-0

Ref. 3D-FD21676

Product Information

• Name: 2,6-Dichlorohydroquinone
• Synonyms: 2,6-Dichloro-1,4-hydroquinone, 1,4-Benzenediol, 2,6-dichloro-, 1,4-Benzenediol, 2,6-dichloro- (9CI), 2,6-Dichloro-1,4-benzenediol, 2,6-Dichloro-4-hydroquinone, 2,6-Dichloro-4-hydroxyphenol, 2,6-Dichloro-p-benzohydroquinone, 2,6-Dichloro-p-hydroquinone, 2,6-Dichlorobenzene-1,4-Diol, Hydroquinone, 2,6-dichloro-, Hydroquinone, 2,6-dichloro- (8CI), Nsc 36936

Description

2,6-Dichlorohydroquinone (2,6-DCQ) is a reactive chemical that has been shown to be cytotoxic and genotoxic in vitro. 2,6-DCQ binds to the thiol group of cysteine residues on the enzyme's active site. This binding changes the redox potential of the molecule and inhibits its activity. 2,6-DCQ also reacts with other proteins in the cell and disrupts their function. This compound is found in high concentrations in samples from wastewater treatment plants. It is also found to be present in some foods such as milk and cheese due to bacterial metabolism.
2,6-DCQ is a metabolite of chlorpyrifos (an insecticide), and it has been shown that it can react with glutathione reductase to form a glutathione adduct which may have toxic effects on cells. The mechanism by which this occurs is not well understood at this time but

• Brand: Biosynth

Chemical properties

• Molecular weight: 179 g/mol
• Formula: C₆H₄Cl₂O₂
• Purity: Min. 95 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C6H4Cl2O2/c7-4-1-3(9)2-5(8)6(4)10/h1-2,9-10H
• InChI key: InChIKey=QQAHQUBHRBQWBL-UHFFFAOYSA-N
• SMILES: Oc1cc(Cl)c(O)c(Cl)c1