Diethylcarbamazine citrate

CAS: 1642-54-2

Ref. 3D-FD21831

Product Information

• Name: Diethylcarbamazine citrate
• Synonyms: N,N-Diethyl-4-methyl-1-piperazinecarboxamide citrate, 1-Diethylcarbamoyl-4-methylpiperazine dihydrogen citrate, 1-Methyl-4-diethylcarbamoylpiperazine citrate, 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, citrate (1:1), Banocide, Caricide, Caritrol, Decc, Dicarocide, Diethyl Carbazine Citrate, Diethyl carbamazine citrate, DiethylCarbazine Citrate, Diethylcarbamazine Acid Citrate, Diethylcarbamazine Dihydrogen Citrate, Dirocide, Ditrazin citrate, Ditrazine, Ethodryl citrate, Ethylaminoazine citrate, Filaribits, Filazine, Franocide, Franozan, Hetrazan, Longicid, Loxuran, N,N-Diethyl-4-methyl-1-piperazinecarboxamide dihydrogen citrate, N,N-diethyl-4-methylpiperazine-1-carboxamide 2-hydroxypropane-1,2,3-tricarboxylate (1:1), NSC 80513

Description

Diethylcarbamazine citrate is an anthelmintic drug that is used to treat helminth infections. It inhibits the growth of nematodes by binding to the polymerase chain and inhibiting protein synthesis. Diethylcarbamazine citrate has been shown to be effective in treating bowel disease, which may be due to its ability to inhibit inhibitor molecules. This drug also has low potency for a number of bacterial species, such as Escherichia coli, Klebsiella pneumoniae, and Bacillus cereus, making it a good choice for use in vitro assays. Diethylcarbamazine citrate has a pyrazole ring in its structure that can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase or conjugated with glucuronic acid.

• Brand: Biosynth

Chemical properties

• Molecular weight: 391.42 g/mol
• Formula: C₁₆H₂₉N₃O₈
• Purity: Min. 95%
• InChI: InChI=1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChI key: InChIKey=PGNKBEARDDELNB-UHFFFAOYSA-N
• SMILES: CCN(CC)C(=O)N1CCN(C)CC1.O=C(O)CC(O)(CC(=O)O)C(=O)O