Difluprednate

CAS: 23674-86-4

Ref. 3D-FD21894

Product Information

• Name: Difluprednate
• Synonyms: (6a,11b)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-pregna-1,4-diene-3,20-dione6a,9-Difluoro-11b,17,21-trihydroxypregn a-1,4-diene-3,20-dione 21-acetate 17-butyrate6a,9-Difluoroprednisolone 21-acetate 17-butyrate, (6Alpha,11Beta)-21-(Acetyloxy)-6,9-Difluoro-11-Hydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Butanoate, (6Alpha,8Xi,10Xi,11Beta,13Xi)-21-(Acetyloxy)-6,9-Difluoro-11-Hydroxy-3,20-Dioxopregna-1,4-Dien-17-Yl Butanoate, (6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione, 21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione (6alpha,11beta)-, 6-Alpha,9α-difluoroprednisolone 21-acetate 17-butyrate, 6-alpha,9-alpha-Difluoroprednisolone 17-butyrate 21-acetate, 6a,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate, 6alpha,9-Difluoro-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate, 6alpha-9-Difluoroprednisolone 21-acetate 17-butyrate, 6α,9-Difluoroprednisolone 21-acetate 17-butyrate, 6α,9α-Difluoroprednisolone 21-acetate 17-butyrate, Butyric acid, 17-ester with 6α,9-difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate, Cm 9155, Difluprednato, Difluprednato [INN-Spanish], Difluprednatum, Difluprednatum [INN-Latin], Durezol, Epitopic, Myser, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6alpha,11beta)-, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6α,11β)-, Pregna-1,4-diene-3,20-dione, 6-alpha,9-difluoro-11-beta,17,21-trihydroxy-, 21-acetate, 17-butyrate, Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-, 21-acetate 17-butyrate, Unii-S8A06Qg2Qe, W 6309

Description

Difluprednate is a corticosteroid that is used topically to treat eye inflammation. It has been shown to reduce ocular inflammation in rats and mice, with no effect on the cornea. Difluprednate is prepared as an aqueous solution containing benzalkonium chloride, which acts as a preservative. The medication can be used for short periods of time, but prolonged use may lead to bowel disease and polymerase chain reactions. Difluprednate has anti-inflammatory activity and can be used in place of nonsteroidal anti-inflammatory drugs (NSAIDs). It has been found that prednisolone acetate, the active form of difluprednate, inhibits inflammatory cells in vitro by inhibiting nuclear factor kappaB activation. This inhibition leads to decreased production of pro-inflammatory cytokines and chemokines such as IL-1β, IL-6, IL-8, T

• Brand: Biosynth

Chemical properties

• Molecular weight: 508.55 g/mol
• Formula: C₂₇H₃₄F₂O₇
• Purity: Min. 95%
• Color/Form: White Powder