3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

CAS: 22246-18-0

Ref. 3D-FD22021

Product Information

• Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
• Synonyms: 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone7-Hydroxy-3,4-dihydrocarbostyril, 2(1H)-Quindinone,3,4-dohydro-7Hydroxy, 2(1H)-Quinolinone, 3,4-dihydro-7-hydroxy-, 3,4-Dihydro-7-Hydroxy-2(1H)-Quinlinone, 3,4-Dihydro-7-hydroxy-2(1 H)-quinoline, 3,4-Dihydro-7-hydroxycarbostyril, 3,4-Dihydro-quinoline-2,7-diol, 3,4-Dihydroquinoline-2,7-diol, 7-Hydroxy carbostyril, 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone, 7-Hydroxy-1,2-Dihydroquinolin-2-One, 7-Hydroxy-2-(1H)-quinolinone, 7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone, 7-Hydroxy-3,4-Dihydro-2-(1H)-Quinoline, 7-Hydroxy-3,4-dihydro-1H-quinolin-2-one, 7-Hydroxy-3,4-dihydrocarbostyril, 7-Hydroxy-3,4-dihydroquinolone, 7-Hydroxycarbostyril, 7-Hydroxyquinolin-2(1H)-One, 7-hydroxy-1H-quinolin-2-one, 7-hydroxy-3,4-dihydroquinolin-2(1H)-one, Carbostyril, 3,4-dihydro-7-hydroxy-, Hydrocarbostyril, 7-hydroxy-

Description

3,4-Dihydro-7-hydroxy-2(1H)-quinolinone is a synthetic compound that has been shown to have antidiabetic activity in vitro. It binds to the alpha2A receptor subtype and inhibits the uptake of chloride ions by cells. 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone also inhibits the uptake of aluminium ions and has been shown to inhibit tumor growth in human nasopharyngeal carcinoma cells. The synthesis of 3,4-dihydro-7-hydroxy-2(1H)-quinolinone is accomplished by reacting aniline with acetophenone and hydrochloric acid in the presence of aluminium chloride and carbostyril. This reaction yields a 50% yield of the desired product.

• Brand: Biosynth

Chemical properties

• Molecular weight: 163.17 g/mol
• Formula: C₉H₉NO₂
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H9NO2/c11-7-3-1-6-2-4-9(12)10-8(6)5-7/h1,3,5,11H,2,4H2,(H,10,12)
• InChI key: InChIKey=LKLSFDWYIBUGNT-UHFFFAOYSA-N
• SMILES: O=C1CCc2ccc(O)cc2N1