5a-Dihydronorethindrone

CAS: 52-79-9

Ref. 3D-FD22040

Product Information

• Name: 5a-Dihydronorethindrone
• Synonyms: 17-Hydroxy-19-norpregn-20-Yn-3-one (5a,17a)
• Brand: Biosynth
• Description: 5a-Dihydronorethindrone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic effects. It has been shown to inhibit the proliferation of human cancer cells by binding to the progesterone receptor, which is involved in the regulation of cell growth. 5a-Dihydronorethindrone has also been shown to bind to aromatase, an enzyme that converts androgens into estrogens. The synthesis of 5a-dihydronorethindrone begins with cholesterol, which is first esterified with acetate. This product then undergoes side-chain cleavage and hydroxylation at C17 to form 17alpha,20beta-dihydroxy-5a-pregnane. The final step in its synthesis involves reduction of the ketone group at C2 to form 2,5alpha dihydronorethindrone.

Chemical properties

• Molecular weight: 300.44 g/mol
• Formula: C₂₀H₂₈O₂
• Purity: Min. 95%