5a-Dihydronorethindrone
CAS: 52-79-9
Ref. 3D-FD22040
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Product Information
- 17-Hydroxy-19-norpregn-20-Yn-3-one (5a,17a)
- (5α,17α)-17-Hydroxy-19-norpregn-20-yn-3-one
- 17.alpha.-Ethynyl-17.beta.-hydroxy-5.alpha.-estran-3-one
- 17α-Ethynyl-17β-hydroxy-5α-estran-3-one
- 17α-Ethynyl-5α-estran-17β-ol-3-one
- 17β-Hydroxy-17α-ethynyl-5α-estran-3-one
- 17β-Hydroxy-19-nor-5α,17α-pregn-20-yn-3-one
- 19-Nor-5α,17α-pregn-20-yn-3-one, 17-hydroxy-
- 19-Norpregn-20-yn-3-one, 17-hydroxy-, (5α,17α)-
- 5α-Dihydronorethindrone
- See more synonyms
- 5α-Dihydronorethisterone
- NSC 85401
- Sts 737
5a-Dihydronorethindrone is a synthetic glucocorticoid with anti-inflammatory and anti-allergic effects. It has been shown to inhibit the proliferation of human cancer cells by binding to the progesterone receptor, which is involved in the regulation of cell growth. 5a-Dihydronorethindrone has also been shown to bind to aromatase, an enzyme that converts androgens into estrogens. The synthesis of 5a-dihydronorethindrone begins with cholesterol, which is first esterified with acetate. This product then undergoes side-chain cleavage and hydroxylation at C17 to form 17alpha,20beta-dihydroxy-5a-pregnane. The final step in its synthesis involves reduction of the ketone group at C2 to form 2,5alpha dihydronorethindrone.
Chemical properties
Technical inquiry about: 3D-FD22040 5a-Dihydronorethindrone
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