Clovamide

CAS: 53755-02-5

Ref. 3D-FD22068

Product Information

• Name: Clovamide
• Synonyms: N-[3',4'-Dihydroxy-(E)-cinnamoyl]-3-hydroxy-L-tyrosine, L-tyrosine, N-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-3-hydroxy-
• CAS: 53755-02-5

Description

Clovamide is an antioxidative agent that has been shown to have immunosuppressant and anti-inflammatory properties. Clovamide has been shown to inhibit acetylcholinesterase and cyclooxygenase, which are enzymes that break down neurotransmitters and prostaglandins, respectively. It also inhibits platelet aggregation, which may be due to its ability to inhibit the synthesis of thromboxane A2. This drug also has a significant antioxidant activity and can reduce lipid hydroperoxides.

Clovamide is used in the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also used for cancer therapy because it causes apoptosis in cancer cells by inhibiting protein synthesis in the cell nucleus and triggering the production of free radicals. The antioxidant properties of clovamide may help protect against cancerous growths or other oxidative damage caused by reactive oxygen species.

• Brand: Biosynth

Chemical properties

• Molecular weight: 359.33 g/mol
• Formula: C₁₈H₁₇NO₇
• Purity: Area-% Min. 95 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C18H17NO7/c20-13-4-1-10(8-15(13)22)3-6-17(24)19-12(18(25)26)7-11-2-5-14(21)16(23)9-11/h1-6,8-9,12,20-23H,7H2,(H,19,24)(H,25,26)/b6-3+/t12-/m0/s1
• InChI key: InChIKey=GPZFXSWMDFBRGS-UXONFWTHSA-N
• SMILES: O=C(/C=C/c1ccc(O)c(O)c1)N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O