3β,5-Dihydroxy-15β,16β-methylene-5β-androst-6-en-17-one

CAS: 82543-15-5

Ref. 3D-FD22073

Product Information

• Name: 3β,5-Dihydroxy-15β,16β-methylene-5β-androst-6-en-17-one
• Synonyms: (3β,5β,15α,16α)-15,16-Dihydro-3,5-dihydroxy-3'H-cycloprop[15,16]androsta-6,15-dien-17-one15β,16β-Methylene-3β,5β-dihydroxyandrost-6 -en-17-one
• Brand: Biosynth
• Description: 3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en-17-one is a steroid hormone that has been shown to have antihypertensive properties. It has been shown to reduce the production of angiotensin II by inhibiting the enzyme angiotensin converting enzyme (ACE). 3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en 17 one has also been shown to be a potent inhibitor of the enzyme 3beta hydroxysteroid dehydrogenase type 1 (3betaHSD1) and 5alpha reductase type 2 (5alphaRD2), which are enzymes that convert cortisone to cortisol and dihydrotestosterone to testosterone respectively. These effects on steroidogenesis may account for its observed antihypertensive activity.

Chemical properties

• Molecular weight: 316.43 g/mol
• Formula: C₂₀H₂₈O₃
• Purity: Min. 95%
• Color/Form: Powder