3,3'-Diiodo-L-thyronine

CAS: 4604-41-5

Ref. 3D-FD22133

Product Information

• Name: 3,3'-Diiodo-L-thyronine
• Synonyms: 3,3'-T2O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine, 3,3′-Diiodo-<span class="text-smallcaps">L</span>-thyronine, 3,5-Diiodo-L-tyrosinedihydrae, <span class="text-smallcaps">L</span>-3,3′-Diiodothyronine, <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-, Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-, <span class="text-smallcaps">L</span>-, O-(4-Hydroxy-3-iodophenyl)-3-iodo-<span class="text-smallcaps">L</span>-tyrosine, L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3-iodo-, L-3,3′-Diiodothyronine, Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-, L-, O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine

Description

3,3'-Diiodo-L-thyronine (T2) is a thyroid hormone that binds to the DNA response element in the promoter region of its target genes. It has been shown to decrease the transcription of genes encoding for proteins involved in energy metabolism and thus may play a role in weight loss. T2 also inhibits the production of hydrochloric acid by human gastric cells, which may lead to a reduction of stomach acidity. T2 is detectable in serum within 3 hours following ingestion and can be quantified using high performance liquid chromatography with electrochemical detection. The matrix effect is a phenomenon that occurs when samples are analyzed using different analytical methods and this must be taken into account when interpreting results. T2 has been shown to have pharmacological effects on experimental animals, including the stimulation of liver cell growth and an increase in metabolic rate.

• Brand: Biosynth

Chemical properties

• Molecular weight: 525.08 g/mol
• Formula: C₁₅H₁₃I₂NO₄
• Purity: Min. 95%
• Color/Form: Powder