3,7-Dimethyl-1-propargylxanthine

CAS: 14114-46-6

Ref. 3D-FD22274

Product Information

• Name: 3,7-Dimethyl-1-propargylxanthine
• Synonyms: DMPX, 3,7-dimethyl-1-(2-propynyl)xanthineNSC 242985
• Brand: Biosynth
• Description: 3,7-Dimethyl-1-propargylxanthine is a cyclase inhibitor that has been shown to have pharmacological effects. It has been shown to be effective in vivo models of Parkinson's disease and has reduced locomotor activity. This drug also inhibits the production of adenosine and dopamine, leading to neuronal death. The 3,7-dimethyl-1-propargylxanthine shows high selectivity for adenosine A3 receptors and is an antagonist at these receptors. It prevents mitochondrial membrane potential from decreasing, which may be due to inhibition of the production of reactive oxygen species by mitochondria. 3,7-Dimethyl-1-propargylxanthine also inhibits platelet aggregation by blocking the activation of phospholipase C and enhances platelet aggregation by inhibiting phosphodiesterase activity.

Chemical properties

• Molecular weight: 218.21 g/mol
• Formula: C₁₀H₁₀N₄O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/CH4/h1H4
• InChI key: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#CCn1c(=O)c2c(ncn2C)n(C)c1=O