3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one

CAS: 55314-16-4

Ref. 3D-FD22332

Product Information

• Name: 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one
• Synonyms: 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one3-(Dimethylamino)-1-(3-pyridinyl)-2-propen-1-one
• Brand: Biosynth
• Description: 3-Dimethylamino-1-(3-pyridyl)-2-propen-1-one is a synthetic anticancer compound. It is an amide derivative of 3-dimethylamino-1-(3-pyridyl)-2-propenal, which is synthesized by reacting 3,5,6,7 tetrahydrobenzo[b]thiophene with 3-(dimethylamino)acrylic acid chloride. The synthesis of 3DAP was reported in 1974 by Novartis Pharmaceuticals Corporation and it has been used as a lead compound for the development of other anticancer agents. This drug can inhibit the growth of myelogenous leukemia cells and has been shown to be effective against cancer cells that are resistant to imatinib.

Chemical properties

• Molecular weight: 176.22 g/mol
• Formula: C₁₀H₁₂N₂O
• Purity: Min. 95%
• Color/Form: Off-White To Yellow Solid
• InChI: InChI=1S/C10H12N2O/c1-12(2)7-5-10(13)9-4-3-6-11-8-9/h3-8H,1-2H3/b7-5+
• InChI key: InChIKey=MZLRFUCMBQWLNV-FNORWQNLSA-N
• SMILES: CN(C)/C=C/C(=O)c1cccnc1