1,4-Dinitrosopiperazine

CAS: 140-79-4

Ref. 3D-FD22439

Product Information

• Name: 1,4-Dinitrosopiperazine
• Synonyms: N,N'-DinitrosopiperazineNSC 339, N,N'-Dinitrosopiperazine, Ai3-21352, Brn 0135106, Ccris 6929, Dnpz, Dinitrosopiperazin, Dinitrosopiperazin [German], Dinitrosopiperazine, Hsdb 5091, N-Dinitrosopiperazine, Nsc 339, Piperazine, 1,4-dinitroso-, Usaf Do-36

Description

1,4-Dinitrosopiperazine is a chemical compound that has been used as an anthelmintic drug and for the treatment of cancer. It is a structural analog of piperazine, but with two nitro groups on each amine group. 1,4-Dinitrosopiperazine can be synthesized from 2,6-diamino-3-nitropyridine and formaldehyde in the presence of sodium nitrite and potassium hydroxide. The reaction mechanism is similar to that of piperazine but with a different product. 1,4-Dinitrosopiperazine can be found in urine samples and reacts with sulfhydryl groups at cysteine residues to form stable adducts. In vitro studies have shown that these adducts inhibit acetylcholinesterase activity and may be responsible for its anticancer properties.
1,4-Dinitrosopiperazine inhibits the growth of squamous carcin

• Brand: Biosynth

Chemical properties

• Molecular weight: 144.13 g/mol
• Formula: C₄H₈N₄O₂
• Purity: Min. 95%
• Color/Form: White To Off-White Solid
• InChI: InChI=1S/C4H8N4O2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H2
• InChI key: InChIKey=WNSYEWGYAFFSSQ-UHFFFAOYSA-N
• SMILES: O=NN1CCN(N=O)CC1