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Doxorubicinone
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Doxorubicinone

CAS: 24385-10-2

Ref. 3D-FD22607

1mg
346.00 €
2mg
452.00 €
5mg
689.00 €
10mg
1,066.00 €
25mg
2,083.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
Doxorubicinone
Synonyms:
  • (8S,10S)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  • (8S-cis)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
Description:

Doxorubicinone is a prodrug that is metabolized to doxorubicin, which has a range of activities against tumour cells. It binds to the hydroxyl group on the enzyme topoisomerase II, preventing DNA unwinding and transcription. Doxorubicinone has been shown to have cardiac toxicity in experimental models and can cause cardiomyopathy in humans. The drug also reduces mitochondrial membrane potential and induces cell lysis.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
414.36 g/mol
Formula:
C21H18O9
Purity:
Min. 95 Area-%
Color/Form:
Red Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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