Dropropizine

Ref. 3D-FD22618

Product Information

• Name: Dropropizine
• Synonyms: 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol(+/-)-Dropropizine
• Brand: Biosynth
• Description: Dropropizine is a natural compound that has been used in the treatment of chronic cough. It has been shown to have anti-inflammatory activity and to suppress the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-8 (IL-8). Dropropizine has also been shown to inhibit the inflammatory response in squamous cell carcinoma. Toxicity studies have shown that dropropizine does not cause any long-term toxicity, even at high doses. In toxicity studies, dropropizine was administered at high doses for up to 6 months with no adverse effects observed. The LD50 of dropropizine is greater than 3 g/kg in rats and mice. Dropropizine has also been found to be safe for use in humans when administered at 10 mg/kg daily for 1 week or 5 mg/kg daily for 2 weeks.; ; Dropropizine inhibits the production of

Chemical properties

• Molecular weight: 236.31 g/mol
• Formula: C₁₃H₂₀N₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2
• InChI key: InChIKey=PTVWPYVOOKLBCG-UHFFFAOYSA-N
• SMILES: OCC(O)CN1CCN(c2ccccc2)CC1