D-102Dye

CAS: 652145-28-3

Ref. 3D-FD22632

Product Information

• Name: D-102Dye
• Synonyms: 5-[[4-[4-(2,2-Diphenylethenyl)phenyl]-1,2,3,3a,4,8b-hexahydrocyclopent[b]indol-7-yl]methylene]-4-oxo-2-thioxo-3-thiazolidineacetic a cid
• CAS: 652145-28-3

Description

D-102Dye is a cationic dye and drug repositioning agent that is used for the treatment of bacterial infections. This compound has been shown to be an active inhibitor of bacterial growth by binding to the surface glycoprotein and inhibiting the transport of nutrients into the cell. D-102Dye binds to the hydrophobic pocket on the outer membrane, forming hydrogen bonds with the phosphate groups found there. The electrochemical impedance spectroscopy studies have shown that this compound inhibits bacterial growth in logarithmic phase cells, but not in stationary phase cells. This may be due to its ability to bind to surface glycoproteins in these different phases. D-102Dye also has high affinity for monoclonal antibodies and methoxy groups, which are present on many proteins and enzymes in mammalian cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 614.78 g/mol
• Formula: C₃₇H₃₀N₂O₃S₂
• Purity: Min. 95%
• InChI: InChI=1S/C37H30N2O3S2/c40-35(41)23-38-36(42)34(44-37(38)43)22-25-16-19-33-31(21-25)29-12-7-13-32(29)39(33)28-17-14-24(15-18-28)20-30(26-8-3-1-4-9-26)27-10-5-2-6-11-27/h1-6,8-11,14-22,29,32H,7,12-13,23H2,(H,40,41)/b34-22-
• InChI key: InChIKey=XGMCROHUTRXETK-VQNDASPWSA-N
• SMILES: O=C(O)CN1C(=O)/C(=C/c2ccc3c(c2)C2CCCC2N3c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)SC1=S