Fluconazole

CAS: 86386-73-4

Ref. 3D-FD23320

Product Information

• Name: Fluconazole
• Synonyms: α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4- triazol -1-yl)methyl]methanolBiozolene, 1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4-triazol-1-yl)methyl]methanol, 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-, 2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol, 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol, Alkanazole, Biozolene, Diflucan, Difluconazole, Elazor, Floroxan, Flucan, Fluconal, Flucostat, Flumycon, Flunazol, Flusol, Flutec, Fluzon, Fungican, Fungicon, Triconal, Triflucan, Uk 49858, Zocon, Zoltec, a.-(2,4-Difluorophenyl)-a-(1H-1,2,4,-triazol-1-ylmethyl)-1H-1,2 ,4-triazole-1-ethanol, α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
• CAS: 86386-73-4

Description

Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).

• Brand: Biosynth

Chemical properties

• Molecular weight: 306.27 g/mol
• Formula: C₁₃H₁₂F₂N₆O
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
• InChI key: InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N
• SMILES: OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F