Product Information
Name:10-DEBC hydrochloride
Synonyms:
- 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride
Brand:Biosynth
Description:10-Deoxy-10-β-D-arabinofuranosylcytosine (10-DEBC) is a chemotherapeutic drug that is used to treat cancers and degenerative diseases. 10-DEBC is an analog of deoxycytidine and it inhibits the synthesis of DNA by competitively inhibiting the ATP binding cassette transporter, leading to cell death by apoptosis or autophagy. It has been shown to be active against B16 mouse melanoma cells in vitro, as well as atp-binding cassette transporter positive cancer cells in vivo. 10-DEBC also inhibits glycogen synthase kinase 3 (GSK3), which regulates autophagy and apoptotic cell death. 10-DEBC has been shown to induce apoptotic cell death in Caco2 cells, a type of human colon adenocarcinoma cell line.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:381.34 g/mol
Formula:C20H25N2OCl·HCl
Purity:Min. 95%
Color/Form:White Powder
Technical inquiry about: 10-DEBC hydrochloride
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