3-(Diethylboryl) pyridine

CAS: 89878-14-8

Ref. 3D-FD29987

Product Information

• Name: 3-(Diethylboryl) pyridine
• Synonyms: 3-(Diethylboranyl)Pyridine, 3-(Diethylboryl)Pyridine, 3-Diethylboropyridine, 3-Pyridinyldiethylborane, 3-Pyridyldiethyl borane, 3-Pyridyldiethylborane, Abiraterone interMediate, Debp, Diethyl(3-(4-Pyridin-3-yl) borane, Diethyl(3-Pyridinyl)-Borane, Diethyl-(pyridin-3-yl)-borane, Diethyl-3-pyridylborane, Dithyl(3-pyridyl)Borane, Pyridine, 3-(diethylboryl)-

Description

3-(Diethylboryl) pyridine is a halogenated biphenyl. It is used in the synthesis of 3-aryl substituted pyridines by cross-coupling reactions with aryl iodides, bromides and chlorides. Cross-coupling reactions are usually carried out at low temperatures (0 to 20°C) in order to minimize side reactions. The reaction is usually conducted in a biphasic system containing an organic solvent and water, which facilitates the extraction of the product from the mixture. 3-(Diethylboryl) pyridine reacts with halide ions via an electrophilic substitution reaction to form a reactive intermediate, which reacts with palladium catalyst to produce the desired product. This process is also called catalytic hydrogenation. 3-(Diethylboryl) pyridine has been shown to inhibit human cytochrome P450 enzymes, which are involved in drug metabolism and break down drugs

• Brand: Biosynth

Chemical properties

• Molecular weight: 147.03 g/mol
• Formula: C₉H₁₄BN
• Purity: Min. 95%
• Color/Form: Powder