5,7-Dihydroxyflavone

CAS: 480-40-0

Ref. 3D-FD30010

Product Information

• Name: 5,7-Dihydroxyflavone
• Synonyms: Chrysin, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, 5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on, 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one, 5,7-Dihydroxy-2-phenylchromen-4-one, 5,7-dihidroxi-2-fenil-4H-benzo[b]piran-4-ona, 5,7-dihydroxy-2-phenyl-4H-benzo[b]pyran-4-one, 5,7-dihydroxy-2-phenyl-4H-benzo[b]pyranne-4-one, Crysin, Flavone, 5,7-dihydroxy-, Nsc 407436, Chrysin-5,7-dihydroxy Flavone, Chrysine, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl-

Description

5,7-Dihydroxyflavone (5,7-DHF) is a flavonoid that has been shown to be an anti-inflammatory cytokine with synergistic effects. It has been shown to inhibit the production of prostaglandin j2 and induce apoptosis in vitro. This compound also has a synergic effect with dinucleotide phosphate, leading to a decrease in DNA fragmentation and neuronal death. The biological properties of 5,7-DHF have been extensively studied in vitro and its anti-inflammatory activity has been confirmed by several studies on animal models. 5,7-DHF also inhibits pro-apoptotic protein expression and promotes neurogenesis in vivo. Synergic effects of 5,7-DHF have also been observed when combined with chrysin or hypoglycemic drugs such as metformin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 254.24 g/mol
• Formula: C₁₅H₁₀O₄
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
• InChI key: InChIKey=RTIXKCRFFJGDFG-UHFFFAOYSA-N
• SMILES: O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12