6,6'-Dibromoindigo

CAS: 19201-53-7

Ref. 3D-FD32493

Product Information

• Name: 6,6'-Dibromoindigo
• Synonyms: (2E)-6,6'-dibromo-2,2'-biindole-3,3'(1H,1'H)-dione, 6,6'-dibromo-2,2'-biindole-3,3'(1H,1'H)-dione, 6,6′-Dibromoindigo, 6,6′-Dibromoindigotin, 6-Bromo-2-(6-bromo-1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro-3H-indol-3-one, 75800, Argaman, Byzantium Purple, Genuine, Imperial Purple [KP], Imperial Purple, Indigotin, 6,6′-dibromo-, Murex Purple, Purple of Mollusca, Purple of the Ancients, Purpurissum [KP], Roman Ostrum, Royal Purple, Tekhelet, Tyrian Purple, [Δ^2,2′-Biindoline]-3,3′-dione, 6,6′-dibromo-
• CAS: 19201-53-7

Description

6,6'-Dibromoindigo is a substrate for enzymes that catalyze the oxidation of aromatic compounds. It can be used to measure the activity of these enzymes in biological samples. 6,6'-Dibromoindigo is also an inhibitor of human pathogens, such as Escherichia coli and Proteus mirabilis. It has been shown to have an apoptotic effect on certain cells in a model system and to inhibit HIV-1 protease. 6,6'-Dibromoindigo binds to the receptors of some bacteria and inhibits their growth by binding to cysteine residues within the bacterial cell wall. This binding prevents formation of the final product from 2 molecules of pyruvic acid, which inhibits oxidative phosphorylation and energy production by mitochondria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 420.06 g/mol
• Formula: C₁₆H₈Br₂N₂O₂
• Purity: Min. 95%
• Color/Form: Purple Powder
• InChI: InChI=1S/C16H8Br2N2O2/c17-7-1-3-9-11(5-7)19-13(15(9)21)14-16(22)10-4-2-8(18)6-12(10)20-14/h1-6,19,21H
• InChI key: InChIKey=UOZOCOQLYQNHII-UHFFFAOYSA-N
• SMILES: O=C1C(c2[nH]c3cc(Br)ccc3c2O)=Nc2cc(Br)ccc21