Product Information
Name:Mertansine
Synonyms:
- N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine DM 1Maytansinoid DM 1
Brand:Biosynth
Description:N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine is a thiol-containing derivative of maytansine. Maytansine and its derivatives kill cells by interfering with the formation of microtubules, and causing the depolymerisation of already formed microtubules. Antibody conjugates of N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine and the murine monoclonal antibody TA. 1, using linkers containing either a disulfide bond or a thioether bond, have been synthesised. These antibody conjugates bind to the HER-2/new oncogene protein that is expressed on human breast tumor cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:738.29 g/mol
Formula:C35H48ClN3O10S
Purity:Min. 95%
Color/Form:White Off-White Yellow Powder
Technical inquiry about: Mertansine
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