Diethyl bromomalonate

CAS: 685-87-0

Ref. 3D-FD35050

Product Information

• Name: Diethyl bromomalonate
• Synonyms: 1,3-Diethyl 2-bromopropanedioate, 2-Bromomalonic acid diethyl ester, 2-Diethyl bromomalonate, Bromomalonic acid diethyl ester, Diethyl 2-bromo-1,3-propanedioate, Diethyl 2-bromomalonate, Diethyl 2-bromopropanedioate, Diethyl Bromopropanedioate, Diethyl α-bromomalonate, Ethyl bromomalonate, Malonic acid, bromo-, diethyl ester, NSC 1985, Propanedioic acid, 2-bromo-, 1,3-diethyl ester, Propanedioic acid, bromo-, diethyl ester, α-Bromomalonic ester

Description

Diethyl bromomalonate is a chemical compound with the formula CHBrOOCCH=COOCH. It is a kinetic data that has been used as a preparative hplc. Coumarin derivatives have been synthesized by its use. This reaction is an example of nucleophilic substitution of diethyl bromomalonate with an alkyl halide and hydrochloric acid in methyl ketones, which are hepg2 cell substrates. The mechanism for this reaction involves formation of an enolate from the carboxylic acid moiety followed by attack of the nucleophile on the electrophilic bromine atom to form the substituted product.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.06 g/mol
• Formula: C₇H₁₁BrO₄
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C7H11BrO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
• InChI key: InChIKey=FNJVDWXUKLTFFL-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(Br)C(=O)OCC