2,4-Dihydroxyquinoline

CAS: 86-95-3

Ref. 3D-FD40531

Product Information

• Name: 2,4-Dihydroxyquinoline
• Synonyms: 2(1H)-Quinolinone,4-hydroxy, 2,4-Dihydroxy quinoline, 2,4-Dihydroxyquinolone, 4-Hydroxy-1,2-dihydro-2-quinolinone, 4-Hydroxy-1H-quinolin-2-one, 4-Hydroxy-2(1H)-Quinolinone, 4-Hydroxy-2(1H)-Quinolone, 4-Hydroxy-2-quinolinone, 4-Hydroxy-2-quinolone, 4-Hydroxycarbostyril, 4-Hydroxyquinolin-2(1H)-One, 4-Hydroxyquinoline-2(1H)-one, Carbostyril, 4-hydroxy-, Dihydroxyquinoline, NSC 12465, NSC 13962, Quinoline-2,4-diol, 2,4-Quinolinediol

Description

2,4-Dihydroxyquinoline is a malonic acid derivative that is used as an antimicrobial agent. It is a diazonium salt that can be synthesized from 2-chloro-4-nitrobenzene and malonic acid. The reaction mechanism for this compound involves the formation of a diazo intermediate, which reacts with the amine to form a quinoline. This compound has been shown to have antibiotic properties and is able to inhibit the growth of bacteria such as Salmonella typhi, Mycobacterium tuberculosis, Escherichia coli, and Staphylococcus aureus. 2,4-Dihydroxyquinoline has also been shown to have anticancer activity in vitro on human liver cells (HepG2) and human hepg2 cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 161.16 g/mol
• Formula: C₉H₇NO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C9H7NO2/c11-8-5-9(12)10-7-4-2-1-3-6(7)8/h1-5H,(H2,10,11,12)
• InChI key: InChIKey=HDHQZCHIXUUSMK-UHFFFAOYSA-N
• SMILES: O=c1cc(O)c2ccccc2[nH]1