5,7-Dibromo-8-hydroxyquinoline

CAS: 521-74-4

Ref. 3D-FD40739

Product Information

• Name: 5,7-Dibromo-8-hydroxyquinoline
• Synonyms: 5,7-Dibromo-8-Hydroxy Quinoline, 5,7-Dibromo-8-quinolinol, 5,7-Dibromooxine, 5,7-Dibromoquinolin-8-Ol, 8-Quinolinol, 5,7-dibromo-, Brodiar, Bromoxin, Broxyquinolin, Broxyquinoline, Colepur, Colipar, Dibromohydroxyquinoline, Dibromoksin, Dibromoquin, Dibromoxin, Dibromoxine, Dibromoxyquinoline, Fenilor, Intensopan, NSC 1810, NSC 74937, Paramiba, Paramibe

Description

5,7-Dibromo-8-hydroxyquinoline is a cytotoxic agent that has been shown to inhibit the growth of xenograft tumor cells. It was found to be effective in inhibiting the mitochondrial membrane potential and decrease the rate of cell proliferation. 5,7-Dibromo-8-hydroxyquinoline also showed significant cytotoxicity against carcinoma cell lines, with no effect on normal human fibroblast cells. The drug is an organophosphate compound that inhibits fatty acid synthesis by binding to an enzyme involved in fatty acid biosynthesis. This inhibition causes diarrhoea and sodium salt loss. 5,7-Dibromo-8-hydroxyquinoline can be extracted from hydrochloric acid through a solvent extraction process.

• Brand: Biosynth

Chemical properties

• Molecular weight: 302.95 g/mol
• Formula: C₉H₅Br₂NO
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
• InChI key: InChIKey=ZDASUJMDVPTNTF-UHFFFAOYSA-N
• SMILES: Oc1c(Br)cc(Br)c2cccnc12