2,3-Dihydro-1,4-benzodioxin-2-ylmethylamine

CAS: 4442-59-5

Ref. 3D-FD42203

Product Information

• Name: 2,3-Dihydro-1,4-benzodioxin-2-ylmethylamine
• Synonyms: (2,3-Dihydro-1,4-benzodioxin-2-yl)methanamine, (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methanamine, (2R)-2,3-dihydro-1,4-benzodioxin-2-ylmethanaminium, (2S)-2,3-dihydro-1,4-benzodioxin-2-ylmethanaminium, (±)-2-(Aminomethyl)-1,4-benzodioxane, 1,4-Benzodioxan, 2-(aminomethyl)-, 1,4-Benzodioxan-2-methylamine, 1,4-Benzodioxane-2-methylamine, 1,4-Benzodioxin-2-methanamine, 2,3-dihydro-, 1-(2,3-Dihydro-1,4-Benzodioxin-2-Yl)Methanamine, 2,3-Dihydro-1,4-benzodioxin-2-methanamine, 2,3-Dihydro-1,4-benzodioxin-2-ylmethanamine, 2,3-Dihydro-1,4-benzodioxin-3-ylmethanamine, 2-(Aminomethyl)-1,4-benzodioxan, 2-Aminomethyl-2,3-dihydro-1,4-benzodioxin, 946F, Aminomethylbenzodioxan, Brn 0150152, Fourneau 946, LP 1 (pharmaceutical), Lp 1, N-[(2,3-Dihydrobenzo[1,4]dioxin-2-yl)methyl]amine, Nsc 116045, [(2,3-Dihydro-1,4-benzdioxin-2-yl)methyl]amine, [(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]amine, 5-19-08-00402 (Beilstein Handbook Reference)

Description

2,3-Dihydro-1,4-benzodioxin-2-ylmethylamine (DHBMA) is a pharmacophore that has been shown to be an epileptic and convulsant in epidemiological studies. This drug binds to the receptor binding site of the Na+/K+ ATPase enzyme and inhibits its binding affinity for sodium ions. DHBMA has been shown to increase blood pressure in rats when it is injected into the cerebral ventricles. DHBMA also increases the affinity for dopamine D2 receptors which are linked to Parkinson's disease. This drug is used as a linker in the synthesis of prenylated synthons, which can be used to produce drugs with high affinity values and stereoisomers.

• Brand: Biosynth

Chemical properties

• Molecular weight: 165.19 g/mol
• Formula: C₉H₁₁NO₂
• Purity: Min. 95%
• Color/Form: Colorless Clear Liquid
• InChI: InChI=1S/C9H11NO2/c10-5-7-6-11-8-3-1-2-4-9(8)12-7/h1-4,7H,5-6,10H2
• InChI key: InChIKey=JHNURUNMNRSGRO-UHFFFAOYSA-N
• SMILES: NCC1COc2ccccc2O1