2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
CAS: 1080622-86-1
Ref. 3D-FD43368
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
2-(6,7-dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine
Description:
2-(6,7-Dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine is an inhibitor drug that is used in the treatment of cancer. It inhibits the growth of cancer cells by binding to their DNA and inhibiting protein synthesis. This drug has been shown to inhibit angiogenesis by reducing the production of VEGF and other proangiogenic factors. 2-(6,7-Dimethoxyquinazolin-4-yl)-5-(pyridin-2-yl)-2H-1,2,4-triazol-3-amine also reduces the production of oncogenes such as cSrc and Akt. It binds to the active site on epidermal growth factor receptor (EGFR) kinase domain that is involved in cell proliferation and survival. The binding causes a conformational change in
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
349.35 g/mol
Formula:
C17H15N7O2
Purity:
Min. 95%
InChI:
InChI=1S/C17H15N7O2/c1-25-13-7-10-12(8-14(13)26-2)20-9-21-16(10)24-17(18)22-15(23-24)11-5-3-4-6-19-11/h3-9H,1-2H3,(H2,18,22,23)
InChI key:
InChIKey=ILBRKJBKDGCSCB-UHFFFAOYSA-N
SMILES:
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OC
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