4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
CAS: 10236-14-3
Ref. 3D-FD58008
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued |
Product Information
Name:
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester
Synonyms:
- Ethyl (E)-4-diethoxyphosphorylbut-2-enoate4-Diethoxyphosphorylbut-2-enoic acid ethyl ester(E)-4-Diethoxyphosphorylbut-2-enoic acid ethyl ester
- 4-Phosphonocrotonic acid triethyl ester~Triethyl trans-4-phosphono-2-butenoate
- ethyl (2E)-4-(diethoxyphosphoryl)but-2-enoate
- ethyl (2E)-2-(diethoxyphosphoryl)but-2-enoate
Description:
4-(Diethoxyphosphinyl)-2-butenoic acid ethyl ester (EDEP) is a selective inhibitor of the transcription factor human leukocyte antigen-1 (HLA-1). It is a stereoselective and potent inhibitor of HIV-1, with an IC50 of 0.8 μM. EDEP has also been shown to be active against cancer cells, including HLA-A2+ breast cancer cells, HL60 leukemia cells, and human cervical cancer cells. This compound is also an inhibitor of quinolizidine alkaloids biosynthesis in plants. EDEP inhibits the synthesis of quinolizidine alkaloids by binding to the nitrogen nucleophile. EDEP can inhibit the activity of coatings that are made from polymers such as polyvinyl chloride (PVC), polyurethane, or epoxy resins.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
250.23 g/mol
Formula:
C10H19O5P
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C10H19O5P/c1-4-13-10(11)8-7-9-16(12,14-5-2)15-6-3/h7-8H,4-6,9H2,1-3H3/b8-7+
InChI key:
InChIKey=LXLODBXSCRTXFG-BQYQJAHWSA-N
SMILES:
CCOC(=O)/C=C/CP(=O)(OCC)OCC
MDL:
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