3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one

Ref. 3D-FD60323

Product Information

• Name: 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one
• Synonyms: Acid Captor H
• Brand: Biosynth
• Description: 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one is a biphenyl derivative that inhibits the HMG-CoA reductase enzyme. It is used to regulate cholesterol levels and has been shown to have a hypoglycemic effect. This drug binds to the active site of HMG-CoA reductase and prevents it from reducing HMG into mevalonate, which prevents the production of cholesterol. 3,4-Dihydro-2H-pyrido[1,2-a]pyrimidin-2-one also binds to the hydroxyl group of a thiazolidine ring and inhibits the enzyme activity of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase. This leads to an increase in endogenous insulin release and decreased blood glucose levels.

Chemical properties

• Molecular weight: 148.16 g/mol
• Formula: C₈H₈N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C8H8N2O/c11-8-4-6-10-5-2-1-3-7(10)9-8/h1-3,5H,4,6H2
• InChI key: InChIKey=XQIOBBHIEUGFCI-UHFFFAOYSA-N
• SMILES: O=C1CCN2C=CC=CC2=N1