4,7-Dimethyl-1,10-phenanthroline
CAS: 3248-05-3
Ref. 3D-FD60893
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- 1,10-Phenanthroline, 4,7-dimethyl-
- 1,8-Dimethyl-4,5-diazaphenanthrene
- 4,7-Dimethy-1,10-Phenathroline
- 4,7-Dimethyl-o-phenanthroline
- Nsc 4281
- Timtec-Bb Sbb008716
4,7-Dimethyl-1,10-phenanthroline (DMPA) is a bifunctional molecule that can act as an electron transfer agent in the mitochondrial respiratory chain. DMPA has been shown to be cytotoxic and pro-apoptotic by inhibiting mitochondrial membrane potential and increasing oxidative stress. DMPA also has anti-cancer properties due to its ability to inhibit nuclear factor kappa-light-chain-enhancer of activated B cells (NFkB). The quinoid moiety of DMPA can undergo oxidation to form a radical cation that may be responsible for its toxicity. DMPA also interacts with hydrogen bonding groups on DNA and other biomolecules.
Chemical properties
Technical inquiry about: 3D-FD60893 4,7-Dimethyl-1,10-phenanthroline
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