3,4-Difluorobenzenethiol

Ref. 3D-FD61255

Product Information

• Name: 3,4-Difluorobenzenethiol
• Synonyms: 3,4-Difluorothiophenol
• Brand: Biosynth
• Description: 3,4-Difluorobenzenethiol is an ester that can be used for chemical ligation. It reacts with primary amines to form a thioester. This reaction also requires a cocatalyst such as pyridine or triethylamine. The resulting thioester can be hydrolyzed to the corresponding alcohol and amine. 3,4-Difluorobenzenethiol is also used in protein synthesis, where it functions as a potent cytotoxic agent. The cytotoxicity of 3,4-difluorobenzenethiol is enhanced by the presence of chloride ions and when reacted with pyridine or triethylamine as cocatalysts. The reaction time is dependent on the type of multivariable technique used.

Chemical properties

• Molecular weight: 146.16 g/mol
• Formula: C₆H₄F₂S
• Purity: Min. 95%
• InChI: InChI=1S/C6H4F2S/c7-5-2-1-4(9)3-6(5)8/h1-3,9H
• InChI key: InChIKey=BGVRHDQMTMPAEZ-UHFFFAOYSA-N
• SMILES: Fc1ccc(S)cc1F