Djenkolic acid

CAS: 498-59-9

Ref. 3D-FD65057

Product Information

• Name: Djenkolic acid
• Synonyms: Djenkolic acid S,S'-Methylenedi-l-cysteine (2R)-2-Amino-3-[[(2R)-2-amino-2-carboxy-ethyl]sulfanylmethylsulfanyl]propanoic acid, (2R,2'R)-3,3'-(methanediyldisulfanediyl)bis(2-aminopropanoic acid) (non-preferred name), 3,3'-(Methanediyldisulfanediyl)Bis(2-Aminopropanoic Acid) (Non-Preferred Name), 3,3'-(Methylenedithio)dialanine, 3,3'-Methylenedithiobis(2-aminopropanoic acid), <span class="text-smallcaps">L</span>-Cysteine, S,S′-methylenebis-, <span class="text-smallcaps">L</span>-Djenkolic acid, Alanine, 3,3'-(methylenedithio)di-, Alanine, 3,3'-(methylenedithio)di-, L- (8CI), Alanine, 3,3′-(methylenedithio)di-, <span class="text-smallcaps">L</span>-, Djenkolate, L-Cysteine thioacetal of formaldehyde, L-Cysteine, S,S'-methylenebis- (9CI), L-Djenkolate, L-Djenkolic acid, Nsc 76076, S,S′-Methylenebis[<span class="text-smallcaps">L</span>-cysteine], beta,beta'-Methylenedithiodialanine, β,β′-Methylenedithiodialanine

Description

Djenkolic acid is a selenium-containing compound that inhibits the bacterial enzyme, β-lactamase. It has been shown to have a broad spectrum of activity against bacteria, including Gram-positive and Gram-negative bacteria. Djenkolic acid is active against many drug resistant strains of bacteria. This compound is a competitive inhibitor of the enzyme and reversibly inhibits β-lactamase, interfering with bacterial protein synthesis. The inhibition of protein synthesis by djenkolic acid is irreversible. Djenkolic acid also has an inhibitory effect on human serum albumin and tissue culture cells but not cell culture. It also has an inhibitory effect on the growth of phytopathogenic fungi such as Phytophthora infestans and Phytophthora sojae. Djenkolic acid shows efficacy in plants such as corn, wheat, barley, oats, rye, cottonwood and poplar trees.

• Brand: Biosynth

Chemical properties

• Molecular weight: 254.33 g/mol
• Formula: C₇H₁₄N₂O₄S₂
• Purity: Min. 95%
• Color/Form: Powder