Product Information
5,7-Dimethoxyindole is a potent inhibitor of the enzyme oxidase. 5,7-Dimethoxyindole has been shown to inhibit the growth of a number of fungi, including Phytophthora infestans and Cryptococcus neoformans. The molecular modeling studies have shown that this molecule can form an H-bond with the acceptor in the active site of the enzyme and prevent access by substrate. This inhibition has been shown to be competitive with respect to ferrous ions and noncompetitive with respect to other cofactors. 5,7-Dimethoxyindole also inhibits integrase enzymes, which are involved in DNA integration during viral replication. 5,7-Dimethoxyindole was found to bind to a pharmacophore model for integrase inhibitors and formylation reactions. This compound is also magnetic due to its high electron density at the methoxy group.
Chemical properties
Technical inquiry about: 3D-FD65790 5,7-Dimethoxyindole
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