4',6'-Dimethoxy-2'-hydroxychalcone

CAS: 1775-97-9

Ref. 3D-FD66669

Product Information

• Name: 4',6'-Dimethoxy-2'-hydroxychalcone
• Synonyms: Cardamonin-4'-methyl ether, (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one, (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, (E)-1-(2-Hydroxy-4,6-Dimethoxy-Phenyl)-3-Phenyl-Propenone, (E)-1-(2-Hydroxy-4,6-dimethoxy-phenyl)-3-phenyl-, (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, (E)-2′-Hydroxy-4′,6′-dimethoxychalcone, 1-(2-Hydroxy-4,6-Dimethoxyphenyl)-3-Phenyl-2-Propen-1-One), 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (2E)-, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (E)-, Cardamonin-4'-Methyl Ether, Chalcone, 2′-hydroxy-4′,6′-dimethoxy-, Dimethoxy-2'-Hydroxychalcone, 4',6'-, Flavokavain B, Flavokavin B, Flavokawain B, Flavokawin B, Persicochalcone

Description

4',6'-Dimethoxy-2'-hydroxychalcone is a flavonoid that has been shown to inhibit autophagy in human leukemia cells (HL-60). It also inhibits the production of nuclear DNA and protein synthesis in bacteria. 4',6'-Dimethoxy-2'-hydroxychalcone has been shown to be an effective inhibitor of the drug transporter P-glycoprotein (Pgp) in vitro, which may be due to its ability to inhibit cyclase activity. This compound has also been shown to have anti-inflammatory properties and has broad spectrum efficacy against a number of infectious diseases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.31 g/mol
• Formula: C₁₇H₁₆O₄
• Purity: Min. 95%
• InChI: InChI=1S/C17H16O4/c1-20-13-10-15(19)17(16(11-13)21-2)14(18)9-8-12-6-4-3-5-7-12/h3-11,19H,1-2H3/b9-8+
• InChI key: InChIKey=QKQLSQLKXBHUSO-CMDGGOBGSA-N
• SMILES: COc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OC)c1