3,5-Dimethoxycinnamide

CAS: 124805-94-3

Ref. 3D-FD67085

Product Information

• Name: 3,5-Dimethoxycinnamide
• Brand: Biosynth
• Description: 3,5-Dimethoxycinnamide is a compound that has been shown to inhibit the C1-4 alkoxy and C1-4 alkyl esterase activity of the enzyme secretase. This enzyme is involved in the production of amyloid beta peptides and is thought to be an important contributor to Alzheimer's Disease. 3,5-Dimethoxycinnamide also inhibits the aspartyl protease activity of aspartyl proteases, which are enzymes that may play a role in Alzheimer's disease. 3,5-Dimethoxycinnamide binds to the hydrophobic region of these enzymes and prevents them from binding to their substrates. The affinity of this compound for these enzymes precludes its ability to bind with other proteins in the brain, thereby reducing its potential toxicity. 3,5-Dimethoxycinnamide can be labeled with halogeno groups or other chemical moieties for profiling purposes.

Chemical properties

• Molecular weight: 207.23 g/mol
• Formula: C₁₁H₁₃NO₃
• Purity: Min. 95%
• InChI: InChI=1S/C11H13NO3/c1-14-9-5-8(3-4-11(12)13)6-10(7-9)15-2/h3-7H,1-2H3,(H2,12,13)/b4-3+
• InChI key: InChIKey=FBRYJRYXVCLPAD-ONEGZZNKSA-N
• SMILES: COc1cc(/C=C/C(N)=O)cc(OC)c1