2,3-Dimethoxy-2'-hydroxychalcone

CAS: 42220-80-4

Ref. 3D-FD67160

Product Information

• Name: 2,3-Dimethoxy-2'-hydroxychalcone
• Synonyms: 2'-Hydroxy-2,3-dimethoxychalcone, 2′-Hydroxy-2,3-dimethoxychalcone, Chalcone, 2′-hydroxy-2,3-dimethoxy-, 2-Propen-1-one, 3-(2,3-dimethoxyphenyl)-1-(2-hydroxyphenyl)-, 3-(2,3-Dimethoxyphenyl)-1-(2-hydroxyphenyl)-2-propen-1-one

Description

2,3-Dimethoxy-2'-hydroxychalcone is a chalcone that has been shown to have anti-tumor activity. It inhibits the function of cancer cells and binds to human liver cancer cells with a structural formula of C14H10O4. This compound also inhibits tumor growth in mice and has been shown to be effective against other types of cancer such as human lung cancer. 2,3-Dimethoxy-2'-hydroxychalcone is active against both estrogen receptor positive and negative breast cancers, although it does not affect normal breast cells. It also functions as an inhibitor of protein kinase C (PKC) in the human liver and may inhibit PKC in other tissues.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.31 g/mol
• Formula: C₁₇H₁₆O₄
• Purity: Min. 95%
• Color/Form: White To Yellow Solid
• InChI: InChI=1S/C17H16O4/c1-20-16-9-5-6-12(17(16)21-2)10-11-15(19)13-7-3-4-8-14(13)18/h3-11,18H,1-2H3/b11-10+
• InChI key: InChIKey=HKKXNGSRSNONCJ-ZHACJKMWSA-N
• SMILES: COc1cccc(/C=C/C(=O)c2ccccc2O)c1OC