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2,6-Dimethoxybenzyl alcohol is a synthetic compound that is a peroxidase substrate. It is used as an alternative for papaverine in the synthesis of penicillin and cephalosporin antibiotics. 2,6-Dimethoxybenzyl alcohol reacts with Mn2+ ions to form hydronium and hydrogen peroxide. This reaction has been shown to be more efficient than the decomposition of hydrogen peroxide by catalases or superoxide dismutases. 2,6-Dimethoxybenzyl alcohol also forms a reactive congener with erythrocytes and plasma proteins that can cause vasoconstriction in the blood vessels. The dimethoxybenzyl group (DMB) is a monosubstituted phenol group that binds to the active site of enzymes such as cytochrome P450s and glutathione reductase.
Chemical properties
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