trans-4,4'-Dihydroxystilbene

CAS: 659-22-3

Ref. 3D-FD70217

Product Information

• Name: trans-4,4'-Dihydroxystilbene
• Synonyms: 1,2-Bis(4-hydroxyphenyl)ethene, 4,4'-(E)-ethene-1,2-diyldiphenol, 4,4'-Dihydroxystilbene, 4,4'-Dioxystilbene, 4,4'-Ethene-1,2-Diyldiphenol, 4,4′-(1,2-Ethenediyl)bis[phenol], 4,4′-Stilbenediol, Nsc 4184, Phenol, 4,4'-(1,2-ethenediyl)bis-, p,p'-Dihydroxystilbene

Description

Trans-4,4'-Dihydroxystilbene is a molecule that has been shown to inhibit the growth of cancer cells in clinical studies. It was found to be more effective than resveratrol and other stilbene derivatives in inhibiting the growth of cancer cells. Trans-4,4'-Dihydroxystilbene also binds to messenger RNA (mRNA) and inhibits protein synthesis. It does this by binding to a specific sequence on mRNA that is involved in the production of proteins for cell division. This binding prevents ribosomes from translating mRNA into protein, thereby inhibiting cell division. Molecular docking analysis revealed that trans-4,4'-Dihydroxystilbene binds to the same region on the growth factor β1 receptor as natural ligands such as glucuronide conjugate or resveratrol. Transfection experiments showed that trans-4,4'-Dihydroxystilbene inhibited the

• Brand: Biosynth

Chemical properties

• Molecular weight: 212.24 g/mol
• Formula: C₁₄H₁₂O₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C14H12O2/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h1-10,15-16H/b2-1+
• InChI key: InChIKey=XLAIWHIOIFKLEO-OWOJBTEDSA-N
• SMILES: Oc1ccc(/C=C/c2ccc(O)cc2)cc1