3,5-Dimethoxybenzhydrazide

CAS: 51707-38-1

Ref. 3D-FD70702

Product Information

• Name: 3,5-Dimethoxybenzhydrazide
• Brand: Biosynth
• Description: 3,5-Dimethoxybenzhydrazide is a combretastatin analogue that binds to tubulin to disrupt the polymerization of microtubules. It has been shown to inhibit tumor cell growth in vitro and in vivo. 3,5-Dimethoxybenzhydrazide has an IC50 of 10 nM for tubulin polymerization, which is significantly lower than colchicine (IC50 of 0.2 μM). This drug also interacts with colchicine binding sites and has a selectivity index of 1.3.

Chemical properties

• Molecular weight: 196.2 g/mol
• Formula: C₉H₁₂N₂O₃
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H12N2O3/c1-13-7-3-6(9(12)11-10)4-8(5-7)14-2/h3-5H,10H2,1-2H3,(H,11,12)
• InChI key: InChIKey=DOWVACHORBOSEF-UHFFFAOYSA-N
• SMILES: COc1cc(OC)cc(C(=O)NN)c1