1,4-Difluoroanthraquinone

Ref. 3D-FD77997

Product Information

• Name: 1,4-Difluoroanthraquinone
• Brand: Biosynth
• Description: 1,4-Difluoroanthraquinone is a synthetic compound that has been shown to have anticancer activity. It can be used to treat cancer by inhibiting the growth of tumor cells. The compound has been shown to react with DNA in human ovarian carcinoma cells and inhibit RNA synthesis in human colon carcinoma cells. 1,4-Difluoroanthraquinone binds to the rRNA of the cancer cells and inhibits protein synthesis, leading to cell death by inhibition of protein synthesis. 1,4-Difluoroanthraquinone was synthesized using a tricycle reaction with alkylation and an asymmetric synthesis method. This process first involved an oxidative coupling reaction that led to the formation of an enol ether. This intermediate was then reacted with propiolic acid catalyzed by copper(II) chloride in ethanol at -78°C in order to yield the desired product.

Chemical properties

• Molecular weight: 244.19 g/mol
• Formula: C₁₄H₆F₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C14H6F2O2/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6H
• InChI key: InChIKey=DTNCXQHDOJRTCD-UHFFFAOYSA-N
• SMILES: O=C1c2ccccc2C(=O)c2c(F)ccc(F)c21