1-(2',4'-Difluorophenyl)-1-(4-piperidinyl) methanone

CAS: 84162-86-7

Ref. 3D-FD93016

Product Information

• Name: 1-(2',4'-Difluorophenyl)-1-(4-piperidinyl) methanone
• Brand: Biosynth
• Description: Risperidone is an antipsychotic drug that is used to treat schizophrenia and other mental disorders. It is a benzisoxazole derivative that has been shown to be an antagonist at dopamine D2, serotonin 5-HT1A, and histamine H1 receptors. Risperidone also has oxime properties. The cyclization of the molecule produces a 4-piperidinol moiety. This can then undergo oxidation by acetonitrile or methyl isobutyl ketone to produce the corresponding methyl isobutyl ketones. These ketones are metabolized in animals by monoamine oxidase (MAO) and cytochrome P450 enzymes such as CYP2D6 and CYP3A4. In humans, risperidone undergoes hydroxylation by CYP3A4, leading to the formation of 4-hydroxyrisperidone, which may contribute to its therapeutic effects.

Chemical properties

• Molecular weight: 225.23 g/mol
• Formula: C₁₂H₁₃NOF₂
• Purity: Min. 95%