4-[(1H-Pyrazol-1-yl)methyl]phenol

CAS: 80200-09-5

Ref. 3D-FDA20009

Product Information

• Name: 4-[(1H-Pyrazol-1-yl)methyl]phenol
• Brand: Biosynth
• Description: 4-[(1H-Pyrazol-1-yl)methyl]phenol (4PMP) is an inhibitor of dopamine beta-hydroxylase that has been studied in assays with dopamine and noradrenaline. It has been shown to activate both noradrenaline and dopamine receptors, and can be used as a tool for the study of blood pressure regulation. 4PMP also increases reactive oxygen species production, which may be due to its ability to react with cyanide ions. The binding of 4PMP to the enzyme is reversible and competitive. The pH profile of 4PMP has also been studied, with a range from 2 to 5.4. Kinetic studies have shown that the reaction rate for 4PMP is best described by a Michaelis-Menten kinetic model, with a Km value of 0.03 mM and Vmax value of 9.3 μM/min for dopamine β-hydroxylase inhibition. There are

Chemical properties

• Molecular weight: 174.2 g/mol
• Formula: C₁₀H₁₀N₂O
• Purity: Min. 95%