N,N-Didesmethyl tamoxifen

CAS: 80234-20-4

Ref. 3D-FDA23420

Product Information

• Name: N,N-Didesmethyl tamoxifen
• Synonyms: (Z)-1-[4-(2-Aminoethoxy)phenyl]-1,2-diphenylbut-1-ene, 2-[4-(1,2-Diphenyl-but-1-enyl)-phenoxy]-ethylamine, 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]ethanamine, Desdimethyltamoxifen, Di-N-demethyltamoxifen, Didemethyltamoxifen, Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-, (Z)-, Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-, Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-, Ici 142268, N,N-Didemethyltamoxifen, N,N-Didesmethyltamoxifen, N-Des(dimethyl)tamoxifen, N-Didesmethyltamoxifen

Description

N,N-Didesmethyl tamoxifen is a metabolite of tamoxifen and belongs to the class of estrogen receptor modulators. It has been shown that this drug binds to liver cells and has a carcinogenic potential in animals. N,N-Didesmethyl tamoxifen is a substrate for cytochrome P450 2D6 (CYP2D6) and is converted to endoxifen. Endoxifen inhibits the growth of cancer cells by binding to estrogen receptors on the cell surface and preventing the natural ligand estradiol from binding with these receptors. The clinical response to tamoxifen treatment may be influenced by genetic polymorphisms in CYP2D6.

• Brand: Biosynth

Chemical properties

• Molecular weight: 343.5 g/mol
• Formula: C₂₄H₂₅NO
• Purity: Min. 95%