Nimesulide-d5
CAS: 1330180-22-7
Ref. 3D-FDC18022
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
Nimesulide-d5 is a 5-fluorinated derivative of nimesulide, which is a nonsteroidal anti-inflammatory drug. Nimesulide-d5 has been shown to have an increased terminal half-life in humans and healthy Chinese subjects, as well as reduced glucuronide conjugate formation. This drug also has an enhanced particle size and improved spectral properties for use in chromatographic applications. Nimesulide-d5 is clinically relevant for the treatment of cancer and acetaminophen induced hepatotoxicity. It is metabolized into its active form by cytochrome P450 enzymes, leading to the inhibition of protein synthesis in cancer cells and the prevention of liver toxicity due to acetaminophen overdose.
Chemical properties
Technical inquiry about: 3D-FDC18022 Nimesulide-d5
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