Product Information
Simurosertib is a molecule inhibitor that inhibits the synthesis of RNA and DNA. It binds to the enzyme polymerase II, which is required for replication of DNA. Simurosertib has been shown to have antitumour activity in vitro and in vivo. It is well-tolerated with an effective dose of 100 mg/kg, which is low relative to other chemotherapy drugs. The drug has potential as an antineoplastic agent against metastatic pancreatic cancer, colorectal cancer, and other cancers that are resistant to current therapies.
Chemical properties
Technical inquiry about: 3D-FDC78276 Simurosertib
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