Ethyl isocyanatoacetate

CAS: 2949-22-6

Ref. 3D-FE01975

Product Information

• Name: Ethyl isocyanatoacetate
• Synonyms: Acetic acid, 2-isocyanato-, ethyl ester, Acetic acid, isocyanato-, ethyl ester, Carbethoxymethyl isocyanate, Ethoxycarbonylmethyl isocyanate, Ethyl N-(oxomethylene)glycinate, Glycine ethyl ester isocyanate, Glycine, N-carbonyl-, ethyl ester, Isocyanatoacetic acid ethyl ester, NSC 56429, NSC 6276, ethyl N-(oxomethylidene)glycinate

Description

Ethyl isocyanatoacetate (EICA) is a fatty acid that has been shown to have antimicrobial activity. It forms coordination complexes with malonic acid and fatty acids, which inhibit the synthesis of proteins by binding to the ribosomes. The antimicrobial properties of EICA are due to its ability to disrupt protein synthesis in gram-negative organisms. EICA also inhibits locomotor activity and levels of human liver enzymes. It has ether linkages as well as sulfonic acid groups, which make it more soluble in water than other fatty acids.
EICA is metabolized by hepatic lipase into methylmalonic acid and ethylmalonic acid, which can lead to metabolic disorders such as alkaptonuria.

• Brand: Biosynth

Chemical properties

• Molecular weight: 129.12 g/mol
• Formula: C₅H₇NO₃
• Purity: Min. 95%
• Color/Form: Liquid
• InChI: InChI=1S/C5H7NO3/c1-2-9-5(8)3-6-4-7/h2-3H2,1H3
• InChI key: InChIKey=DUVOZUPPHBRJJO-UHFFFAOYSA-N
• SMILES: CCOC(=O)CN=C=O