Ethyl cyclopentanone-2-carboxylate

CAS: 611-10-9

Ref. 3D-FE03363

Product Information

• Name: Ethyl cyclopentanone-2-carboxylate
• Synonyms: Ethyl 2-oxocyclopentanecarboxylate, (.+-.)-2-Oxocyclopentanecarboxylic acid ethyl ester, 1-Oxocyclopentane-2-carboxylic acid ethyl ester, 2-(Ethoxycarbonyl)-1-cyclopentanone, 2-(Ethoxycarbonyl)cyclopentanone, 2-Carbethoxy-1-cyclopentanone, 2-Carbethoxycyclopentanone, 2-Carboethoxycyclopentanone, 2-Cyclopentanonecarboxylic acid ethyl ester, 2-Oxociclopentanocarboxilato De Etilo, 2-Oxocyclopentane-1-carboxylic acid ethyl ester, 2-Oxocyclopentanecarboxylate D'Ethyle, Ethyl (.+-.)-2-oxocyclopentanecarboxylate, Ethyl 1-oxocyclopentane-2-carboxylate, Ethyl 2-cyclopentanone-1-carboxylate, Ethyl 2-cyclopentanonecarboxylate, Ethyl 2-oxo-1-cyclopentanecarboxylate, Ethyl 2-oxocyclopentanoate, Ethyl 2-oxocyclopentylcarboxylate, Ethyl-2-oxocyclopentancarboxylat, Nsc 22055, Nsc 5658, α-(Carboethoxy)cyclopentanone
• CAS: 611-10-9

Description

Ethyl cyclopentanone-2-carboxylate (ECPC) is a chemical compound that can be synthesized from picolinic acid, β-amino acid, and methyl ketones. It is a bifunctional molecule that has been shown to have the ability to activate methylene groups. ECPC has been used in the synthesis of β-amino esters and ethyl esters. This compound can also react with hydrogen fluoride and trifluoroacetic acid to form ethyl cyclopentanone-2-carboxylate trifluoroacetate (ECPCT). ECPC has been found to undergo an aldol cyclization reaction when exposed to hydrogen ions in the presence of a base. The activation energies for this reaction are 19.6 kJ/mol for the first step and 23.5 kJ/mol for the second step.

• Brand: Biosynth

Chemical properties

• Molecular weight: 156.18 g/mol
• Formula: C₈H₁₂O₃
• Purity: Min. 95 Area-%
• Color/Form: Colorless Clear Liquid
• InChI: InChI=1S/C8H12O3/c1-2-11-8(10)6-4-3-5-7(6)9/h6H,2-5H2,1H3
• InChI key: InChIKey=JHZPNBKZPAWCJD-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1CCCC1=O