Oxyma

CAS: 3849-21-6

Ref. 3D-FE04090

Product Information

• Name: Oxyma
• Synonyms: Ethyl (hydroxyimino)cyanoacetateEthyl oximinocyanoacetateEthyl isonitrosocyanoacetate, 2-Cyano-2-(hydroxyimino)acetic acid ethyl ester, Acetic acid, 2-cyano-2-(hydroxyimino)-, ethyl ester, Acetic acid, cyano(hydroxyimino)-, ethyl ester, Ethyl (Hydroxyimino)Cyanoacetate, Ethyl 2-(Hydroxyimino) Cyanoacetate, Ethyl 2-(Hydroxyimino)-3-Nitrilopropanoate, Ethyl 2-cyano-2-(hydroxyimino)acetate, Ethyl 2-cyano-2-(hydroxyimino)ethanoate, Ethyl 2-cyano-2-oxidoiminoacetate, Ethyl 2-cyano-2-oximinoacetate, Ethyl 2-hydroxyimino-2-cyanoacetate, Ethyl Cyanoglyoxylate Oxime, Ethyl Cyanoglyoxylate-2-Oxime, Ethyl Oximinocyanoacetate, Ethyl cyanoglyoxalate-2-oxime, Ethyl cyanoximidoacetate, Ethyl isonitrosocyanoacetate, Ethyl α-cyano-α-oximinoacetate, Ethyl2-cyano-2-oximinoacetate, Ethyl[Hydroximino]Cyanoacetate, Ethylcyanoglyoxylate-2-oxime=Ethyloximinocyanoacetate, Glyoxylic acid, cyano-, ethyl ester, 2-oxime, Glyoxylic acid, cyano-, ethyl ester, oxime, Isonitrosocyanoacetic Acid Ethyl Ester, NSC 137667, NSC 41021, NSC 42116, Oximinocyanoaceticacidethylester, Oxyma Pure, Timtec-Bb Sbb007937, ethyl (2E)-cyano(hydroxyimino)ethanoate, ethyl (2Z)-cyano(hydroxyimino)ethanoate

Description

Ethyl isonitrosocyanoacetate, generally known as Oxyma or OxymaPure, is an additive used in amide coupling reactions as a racemisation suppressant. Oxyma is a safe alternative to the explosive HOAt and HOBt and is mainly used in combination with the carbodiimides EDCI, DCC or DIC. Oxyma is stable, can be used in solution, solid-phase and microwave-assisted synthesis, has great capacity to inhibit epimerisation, excellent coupling efficiencies and shows no risk of capping the resin or the peptide upon hydrolysis of the ethyl ester.

• Brand: Biosynth

Chemical properties

• Molecular weight: 142.11 g/mol
• Formula: C₅H₆N₂O₃
• Purity: Min. 98 Area-%
• Color/Form: Powder
• SMILES: CCOC(=O)/C(C#N)=N/O