N6-Ethenoadenine

CAS: 13875-63-3

Ref. 3D-FE08004

Product Information

• Name: N6-Ethenoadenine
• Synonyms: 1,N(6)-Ethenoadenine, 1,N⁶-Ethenoadenine, 1,N⁶-Ethyleneadenine, 1H-Imidazo(2,1-i)purine, 3H-Imidazo[2,1-i]purine, Ethenoadenine, ε-Adenine, 1,N6-Ethyleneadenine

Description

N6-Ethenoadenine is a nucleoside that is generated during DNA repair. It is formed by the enzymatic activity of the enzyme N6-adenosyltransferase in the presence of ATP and S-adenosylmethionine. It has been shown to be a potent inducer of DNA damage and mutagenesis, as well as an inhibitor of polymerase chain reaction (PCR) and DNA replication. N6-Ethenoadenine is also an agonist for P2Y receptors, which are important in chemical biology. This nucleoside may serve as a potential biomarker for genotoxic events, such as chemotherapy treatments or exposure to ionizing radiation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 159.15 g/mol
• Formula: C₇H₅N₅
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C7H5N5/c1-2-12-4-11-6-5(7(12)8-1)9-3-10-6/h1-4H,(H,9,10)
• InChI key: InChIKey=OGVOXGPIHFKUGM-UHFFFAOYSA-N
• SMILES: c1cn2cnc3nc[nH]c3c2n1