6-Ethylmercaptopurine

CAS: 5417-84-5

Ref. 3D-FE08008

Product Information

• Name: 6-Ethylmercaptopurine
• Synonyms: 6-Ethylthiopurine, 1H-Purine, 6-(ethylthio)-, 6-(Ethylthio)-9H-purine, 6-(Ethylthio)purine, 6-(ethylsulfanyl)-5H-purine, 6-(ethylsulfanyl)-7H-purine, 6-Ethyl MP, 9H-Purine, 6-(ethylthio)-, Ai3-50227, Nsc 11588, Purine, 6-(ethylthio)-, Qa 69

Description

6-Ethylmercaptopurine is a purine analogue that inhibits the synthesis of DNA. It is used as an inhibitor of protein synthesis and in the treatment of inflammatory bowel disease. 6-Ethylmercaptopurine has been shown to inhibit the activity of ATPase, which may be responsible for its ability to suppress the proliferation of cells. This drug can also act as an analog to adenosine, which can be used to determine ATP levels in a cell or tissue sample by measuring the amount of p-nitrophenyl phosphate produced. 6-Ethylmercaptopurine has been shown to block phosphatase activity, which may lead to inflammation in some cases.
6-Ethylmercaptopurine has a molecular weight of 194.2 g/mol and an optimum pH of 4.5

• Brand: Biosynth

Chemical properties

• Molecular weight: 180.23 g/mol
• Formula: C₇H₈N₄S
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C7H8N4S/c1-2-12-7-5-6(9-3-8-5)10-4-11-7/h3-4H,2H2,1H3,(H,8,9,10,11)
• InChI key: InChIKey=XTJLAIOQORFEOI-UHFFFAOYSA-N
• SMILES: CCSc1ncnc2nc[nH]c12