Ethyl pyrazole-4-carboxylate

CAS: 37622-90-5

Ref. 3D-FE11075

Product Information

• Name: Ethyl pyrazole-4-carboxylate
• Synonyms: 1H-Pyrazol-4-carboxylic acid ethyl ester, 1H-Pyrazole-4-carboxylic acid ethyl ester, 1H-pyrazol-4-yl propanoate, 4-Ethoxycarbonyl-1H-pyrazole, 4-Ethoxycarbonylpyrazole, Ethyl 4-pyarazolecarboxylate, Ethyl 4-pyrazole carboxylate, Pyrazole-4-carboxylic acid, ethyl ester, ethyl 1H-pyrazole-4-carboxylate, Ethyl 4-pyrazolecarboxylate

Description

Ethyl pyrazole-4-carboxylate is a low yield, transition metal salt that is used in the synthesis of pyrazoles. It can be synthesized by the reaction of sodium ethoxide with ethyl chloroformate and a Grignard reagent. Sodium ethoxide is added to a suspension of sodium chloride and dried ethyl chloroformate, followed by addition of magnesium turnings. The mixture is refluxed for one hour, cooled, and filtered to give crystals. Ethyl pyrazole-4-carboxylate is used in the preparation of ethyl esters from aliphatic alcohols by reacting with boron trichloride or phosphorus pentachloride. It participates in certain chemical reactions as a byproduct and can damage equipment during chemical reactions. The yield of this compound can be increased by using an excess amount of Grignard reagent or adding hexamethylenetetramine to the reaction mixture

• Brand: Biosynth

Chemical properties

• Molecular weight: 140.14 g/mol
• Formula: C₆H₈N₂O₂
• Purity: Min. 95%
• Color/Form: Powder